Supplements for Anxiety and Constant Worry: What Reddit Users Report
This ranking reflects what people who describe anxiety or constant worry report in Reddit comments: 555 owner comments, ranked by a context rating that shrinks small samples toward the average. It is not a recommendation to try any of them. Persistent or severe symptoms need a doctor's assessment. Vitamin D and B vitamins are left out as background pages.
Many people in these threads also take prescription medicine. We do not score or rank prescription drugs, and supplements are not a substitute for care from a doctor or therapist. If you take an antidepressant, read serotonin supplements and antidepressants.
| # | Supplement | Context rating | Rated comments here | Positive | Negative | Overall score |
|---|---|---|---|---|---|---|
| 1 | Saffron extract (incl. Affron) | 4.0 | 25 | 23 | 2 | 4.0 |
| 2 | Lavender oil capsules (Silexan / Lavela) | 3.8 | 3 | 3 | 0 | 3.6 |
| 3 | Valerian root | 3.7 | 6 | 5 | 0 | 3.4 |
| 4 | Passionflower | 3.7 | 3 | 3 | 0 | 4.0 |
| 5 | GABA | 3.6 | 7 | 6 | 1 | 3.1 |
| 6 | Methylfolate (L-methylfolate) | 3.6 | 7 | 5 | 1 | 3.2 |
| 7 | L-theanine | 3.5 | 46 | 35 | 10 | 4.0 |
| 8 | Magnesium L-threonate (Magtein) | 3.5 | 4 | 3 | 1 | 3.5 |
| 9 | 5-HTP | 3.5 | 4 | 3 | 1 | 3.5 |
| 10 | Taurine | 3.5 | 9 | 7 | 2 | 3.7 |
| 11 | Lemon balm | 3.4 | 3 | 2 | 1 | 3.6 |
| 12 | Inositol | 3.4 | 3 | 2 | 1 | 3.5 |
| 13 | Magnesium (form not stated) | 3.3 | 67 | 43 | 19 | 4.1 |
| 14 | Chamomile | 3.3 | 8 | 5 | 2 | 4.0 |
| 15 | Omega-3 / fish oil (EPA/DHA) | 3.2 | 5 | 2 | 2 | 3.2 |
| 16 | Magnesium glycinate | 3.2 | 75 | 43 | 23 | 4.0 |
| 17 | NAC (N-acetylcysteine) | 3.2 | 24 | 12 | 8 | 3.2 |
| 18 | Magnolia bark (incl. Relora) | 3.2 | 3 | 1 | 2 | 3.6 |
| 19 | Glycine | 3.0 | 11 | 5 | 6 | 3.0 |
| 20 | St John's wort | 2.8 | 5 | 0 | 3 | 2.8 |
For quick shortlists by concern, see which calm supplements Reddit owners rate highest. Still comparing? Browse every calm supplement we track, sorted by Reddit owner score. Unsure where to begin? See how to narrow down anxiety supplements.
In their words
4/5 Mood“Can't speak for depression for i have used sam-e for anxiety, paired with saffron and nac, felt better and greatly helped boost mood levels.”
4/5 Taste & form“If you're ever interested in a “natural” solution two other things that have worked for me are natures bounty anxiety and stress and/or lavender oil capsules(not to be confused with aromatherapy)”
4/5“I took valerian root to curb the anxiety two days ago and that seems to be helping so far… we'll see.”
4/5 Taste & form“Chamomile and passion flower tea helped me I'd drink it half hour before I'd smoke and boom the anxiety stopped I don't know…why I found this out by accident but give it a try”
Mixed and negative reports
2/5 Side effects“I've tried ashweghanda & saffron and neither worked for me either..i had a particularly bad reaction to ash it just made my anxiety way worse”
2/5“Any time I try any dose of l-methyl folate, I get anxiety and insomnia is worse.”
Rankings by type and common questions
- Best Magnesium for Anxiety and Constant Worry
- Best Amino Acid Supplement for Anxiety and Constant Worry
- Best Herbal Supplement for Anxiety and Constant Worry
- Does magnesium glycinate help with anxiety?
- Does magnesium help with anxiety?
- Does L-theanine help with anxiety?
- Does saffron help with anxiety?
Before you try anything
- Start one supplement at a time so you can tell what made a difference.
- Do not stop or change a prescribed medicine on your own.
- Check interactions with any medicine you take: safety and interactions guide.
- Background reading: How to Choose a Calm Supplement.