Medical disclaimer: CalmVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you take an antidepressant or other medicine, are pregnant, or have a medical condition. Do not stop or change prescribed medicine on your own. If you are in crisis or thinking about suicide, call or text 988 (US) or your local emergency number. Full disclaimer.

Calming herbs · capsules

Apigenin: What People With Stress, Anxiety or Low Mood Report on Reddit

Illustration, not a product photo.

A flavonoid found in chamomile, sold as capsules.

3.1 CalmVerdict score

6 owner comments (3 with a clear rating) from r/sleep, r/Supplements, r/insomnia, May 2026 to October 2026. Top 84% of the 24 ranked supplements.

Owner sentiment3.4

Recommendations1.0

Tolerability3.9

ValueNot rated

Value: Not rated. The example products differ too much in dose to compare cost fairly. How we score.

The short version

Apigenin is rated below most supplements we track: 3.1/5. Of 3 rated owner comments, 2 were positive, 0 mixed and 1 negative; 1 mention an unwanted effect. People talk most about calming effect and side effects.

Reddit comments are self-reported and unverified. They tell you what people noticed, not whether a supplement works or is safe for you.

Here is how the calming herbs differ in owner reports. Our stress supplement shortlists group top-rated options by what people report. You can also compare all rated mood supplements on one page.

What it is

Apigenin is a flavonoid found in chamomile, parsley and celery. Human trials of apigenin on its own for sleep or anxiety are scarce.^[PubMed]

What Reddit owners say

Commonly praised

Calming effect: 1 owner comment

Common complaints

Calming effect: 1 owner comment
Side effects: 1 owner comment

4/5 Calming effect
“i take futuro labs apigenin now, it's a natural supplement that helps with relaxation and actually getting to sleep, and it's taken the edge off enough that i'm not hitting that wall as often.”

owner comment via r/insomnia · 2026-05-13 · 2 upvotes

4/5
“i take futuro labs apigenin (helps with relaxation and winding down) and cleaned up my evenings a bit and that combo did more than either alone.”

owner comment via r/sleep · 2026-05-13 · 1 upvotes

2/5 Calming effectSide effects
“The weird thing is for me that l-theanine, despite noticably calming overstimulation during the day, seems to make my sleep more shallow/keep me up all night if taken in the evening, and apigenin can sometimes do fine (nothing…”

owner comment via r/sleep · 2026-05-05 · 1 upvotes

Example products

These are examples of Apigenin products sold on Amazon. They are not ranked by Reddit and the score above is for the ingredient, not a specific product. Check the label for dose and other ingredients.

Example product · not Reddit-scored

Nutricost Apigenin 50mg, 180 Capsules

Price varies; check Amazon for the current price.

Check Price on Amazon

Example product · not Reddit-scored

Nootropics Depot Apigenin Capsules, 50mg, 60 Count

$19.99 on Amazon (price as of 2026-11-03). Prices change; check Amazon for the current price.

Check Price on Amazon

Research to read

Published studies (we list them so you can read the evidence yourself; inclusion is not an endorsement):

Front Nutr 2024: Apigenin: a natural molecule at the intersection of sleep and aging.

FAQ

What do people say about Apigenin for stress, anxiety or mood on Reddit?

Across 6 Reddit comments from people who say they have used it, 2 of 3 rated comments were positive and 1 negative, for a CalmVerdict score of 3.1/5. These are self-reported experiences, not clinical evidence.

Do people report side effects with Apigenin?

1 of 3 rated owner comments (33%) describe an unwanted effect such as drowsiness, headache, stomach upset or feeling flat. Check the safety notes on this page and ask a doctor or pharmacist before starting.

Is Apigenin scored on clinical evidence?

No. The score summarizes Reddit owner comments only. Factual statements on this page link to NIH or PubMed sources, and nothing here is medical advice.