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Supplements for Panic Attacks: What Reddit Users Report

This ranking reflects what people who mention panic attacks report in Reddit comments: 121 owner comments, ranked by a context rating that shrinks small samples toward the average. It is not a recommendation to try any of them. Persistent or severe symptoms need a doctor's assessment. Vitamin D and B vitamins are left out as background pages.

Many people in these threads also take prescription medicine. We do not score or rank prescription drugs, and supplements are not a substitute for care from a doctor or therapist. If you take an antidepressant, read serotonin supplements and antidepressants.

#SupplementContext ratingRated comments herePositiveNegativeOverall score
1Saffron extract (incl. Affron)3.84404.0
2L-theanine3.6131124.0
3Valerian root3.64303.4
4Magnesium glycinate3.512824.0
5Omega-3 / fish oil (EPA/DHA)3.23123.2
6Magnesium (form not stated)2.915684.1
7Magnesium L-threonate (Magtein)2.86153.5

In their words

4/5

“Magnesium Glycinate helps hun & Cbt too...something is triggering you to stay in fight or flight but there is true help out there♡ I personally use saffron and omg it's helped immensely!”

owner comment via r/Anxiety · 2026-09-04 · 3 upvotes
4/5 Side effects

“I swear by L-Theanine making my social interaction flow a lot smoother.”

owner comment via r/Nootropics · 2026-06-13 · 11 upvotes
4/5 Taste & form

“I started taking valeriana root pills daily and I never had panic attacks again.”

owner comment via r/Anxiety · 2026-06-07 · 7 upvotes
4/5

“Magnesium Glycinate helps hun & Cbt too...something is triggering you to stay in fight or flight but there is true help out there♡ I personally use saffron and omg it's helped immensely!”

owner comment via r/Anxiety · 2026-09-04 · 3 upvotes

Mixed and negative reports

2/5 Side effects

“Until a day after I took L theanine. Started with brain fog then became thought loops and full blown panic attack with full physical symptoms and havnt been the same since.”

owner comment via r/Supplements · 2026-10-04 · 1 upvotes
2/5

“2.Magnesium Glycinate - Gives me a panic attack every single time.”

owner comment via r/Supplements · 2026-09-08 · 8 upvotes

Before you try anything